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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR1D1 All Species: 14.85
Human Site: Y503 Identified Species: 29.7
UniProt: P20393 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20393 NP_068370.1 614 66805 Y503 M F L S R T T Y S L Q E L G A
Chimpanzee Pan troglodytes XP_516330 579 64584 V471 L S G K K Y S V D D L H S M G
Rhesus Macaque Macaca mulatta O18924 505 57572 E397 D F M E P K F E F A V K F N A
Dog Lupus familis XP_542763 576 64407 Y466 T F L S G K K Y S V D D L H S
Cat Felis silvestris
Mouse Mus musculus Q3UV55 615 66784 Y504 M F L S R T T Y S L Q E L G A
Rat Rattus norvegicus Q63503 615 66675 Y504 M F L S R T T Y S L Q E L G A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509051 657 72899 F547 T F L S G K K F S V D D L H S
Chicken Gallus gallus O42101 501 57084 E393 N L M S H A Q E L V A K L R S
Frog Xenopus laevis P37234 477 54037 E369 D F M E P K F E F A I R F N S
Zebra Danio Brachydanio rerio NP_991292 637 69439 Y527 T F I S G A T Y S L E A L K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17671 1199 128515 G1002 A A S S T T N G V G N R S P S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9XUK7 514 56114 M406 H S D R L R Q M S Q I S Q H F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.1 22.7 50.3 N.A. 95.6 94.8 N.A. 45.5 21 25.4 58.8 N.A. 20.6 N.A. 25.5 N.A.
Protein Similarity: 100 63 39.9 63.1 N.A. 97 96.7 N.A. 58.9 33 40.3 67.9 N.A. 31.1 N.A. 41.2 N.A.
P-Site Identity: 100 0 13.3 40 N.A. 100 100 N.A. 33.3 13.3 6.6 46.6 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 20 26.6 60 N.A. 100 100 N.A. 60 40 20 66.6 N.A. 20 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 17 0 0 0 17 9 9 0 0 34 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 0 9 0 0 0 0 0 9 9 17 17 0 0 0 % D
% Glu: 0 0 0 17 0 0 0 25 0 0 9 25 0 0 0 % E
% Phe: 0 67 0 0 0 0 17 9 17 0 0 0 17 0 9 % F
% Gly: 0 0 9 0 25 0 0 9 0 9 0 0 0 25 9 % G
% His: 9 0 0 0 9 0 0 0 0 0 0 9 0 25 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 17 0 0 0 0 % I
% Lys: 0 0 0 9 9 34 17 0 0 0 0 17 0 9 0 % K
% Leu: 9 9 42 0 9 0 0 0 9 34 9 0 59 0 0 % L
% Met: 25 0 25 0 0 0 0 9 0 0 0 0 0 9 0 % M
% Asn: 9 0 0 0 0 0 9 0 0 0 9 0 0 17 0 % N
% Pro: 0 0 0 0 17 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 17 0 0 9 25 0 9 0 0 % Q
% Arg: 0 0 0 9 25 9 0 0 0 0 0 17 0 9 0 % R
% Ser: 0 17 9 67 0 0 9 0 59 0 0 9 17 0 50 % S
% Thr: 25 0 0 0 9 34 34 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 9 9 25 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _